My experience switching from Windows to Linux Mint as my main OS has been a little rough at first, but I've fully adjusted by now and I'm really comfortable with this new working environment. It's surprising how user-friendly this particular distro is for Linux newcomers. I haven't run into any major problems so far and everything has worked out of the box, from media codecs to hardware drivers (even my Wacom tablet was plug and play)!
What I really appreciate about Linux is the multitude of free and open source applications available for creating art: MyPaint and Krita for digital painting, Inkscape for vector art, GIMP for post-process image editing and Blender for 3D modeling and animation (plus game development). I'm not yet fully proficient at using all the features these programs have to offer, but it only goes to show how much potential they have for those who are willing to learn how to use them.
Other artists like TysonTan
have shown exactly what can be done using open-source art programs with the exceptional works they've put up in their galleries:
Both artists have inspired me to try and create art using free and open-source software as much as possible, starting with using only MyPaint and GIMP for my most recent submissions.
Though I wouldn't exactly do away with what I can already create using proprietary software. I'd like to continue working on Flash submissions, and my preferred program for pixel art is not open source. Still, if there's an open source alternative for a particular work flow, then I'm willing to learn new things.